Comparative antibacterial activity of silver nanoparticles from Blumia lacera and Neolamarckia cadamba against methicillin-resistant Staphylococcus aureus
DOI:
https://doi.org/10.71336/jabs.1371Keywords:
AgNPs, Ultraviolet visible spectroscopy, ethicillin-resistant Staphylococcus aureus (MRSA), Green synthesis, Antimicrobial activityAbstract
Silver nanoparticles (AgNPs) have shown promise as antibiotic-free antibacterial agents. This study comparatively evaluates the antibacterial activity of AgNPs synthesized from Blumia lacera and Neolamarckia cadamba against methicillin-resistant Staphylococcus aureus (MRSA). Staphylococcus aureus isolates obtained from various clinical samples, including wound swabs and pus, were phenotypically and genotypically confirmed as MRSA. AgNPs were characterized using UV-visible spectroscopy, and their antibacterial efficacy was assessed via disc diffusion, agar cup methods, and time-kill curves. Results demonstrated that Blumia lacera AgNPs exhibited remarkably significant (P < 0.009) antibacterial activity by showing greater zones of inhibition compared to Neolamarckia cadamba. These findings highlight the potential of green-synthesized AgNPs as effective agents against MRSA.
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